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1229236-86-5
TL13-110 also prompts the degradation of additional kinases including Aurora A
Molecular Weight: 548
BMS-626529 had half-maximal effective concentration (EC(50)) values of <10 nM against the vast majority of viral isolates
AEE788 has significantly smaller tumors and complete inhibition of lymph node metastasis
GNE-477 - CAS# 1032754-81-6 Catalog No.:M10487-2 1229236-86-5GNE 477 is a dual inhibitor of PI3K (IC50 = 4 nM for PI3K) and mTOR (apparent Ki = 21 nM). Product information CAS Number: 1032754 81 6 Molecular Weight: 504. 63 Formula: C21H28N8O3S2 Synonym: GNE477 GNE 477 Chemical Name: 5 {6 [(4 methanesulfonylpiperazin 1 yl)methyl] 7 methyl 4 (morpholin 4 yl)thieno[3,2 d]pyrimidin 2 yl}pyrimidin 2 amine Smiles: CC1C2=NC(=NC(=C2SC=1CN1CCN(CC1)S(C)(=O)=O)N1CCOCC1)C1=CN=C(N)N=C1 InChiKey: AKKCGLXULFRAET UHFFFAOYSA N
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